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KMID : 0377520160410020035
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Chung-Ang Journal of Medicine
2016 Volume.41 No. 2 p.35 ~ p.41
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The Improving Effects of Ceratonia siliqua Extracts on Androgen Deficiency in Aging Male
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Yin Fu Yin
Noh Yoo-Hun
Lee Seung-Ah
Jeong Jae-Hun
Kim Kyung-Yong
Han Seung-Ho
Lee Won-Bok
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Abstract
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As men age, andropause is the gradual decline in testosterone production with increasing age. The symptoms of andropause include the loss of physical and psychological activity. Some studies of anti-andropause therapy have mentioned significant process in reducing the symptoms, but, the effects of natural substances are not fully studied. The objective of this study was to examine the effect of carob (Ceratonia Siliqua L.) extract on the symptoms of andropause by increasing serum testosterone levels and reducing andropause symptoms. Carob which belongs to the legume family, contains many vitamins and minerals, and has a high dietary fiber and protein content. We studied the effect of carob on 13-month-old aging male rats. After daily administration of carob for 4 weeks, testosterone levels, sperm counts, motor coordination were increased. Additionally, body weight and body fat mass were decreased in carob-fed groups compared with in untreated groups. Carob did not affect testicle weight, aspartate aminotransferase and alanine aminotransferase levels. Overall, these results suggest that carob is a safe and effective natural substance for the relief of andropause symptoms and may also improve a wide variety of other symptoms.
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KEYWORD
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Carob, Andropause, Testosterone, Sperm count, Motor function
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